(Download) Indian National Biology Olympiad (INBO) Question Papers 2012

Question paper
Exam Name : INBO Olympiad Question Papers 2012

Section A

1. (1 point) According to the current concept of Central Dogma of molecular biology, information transfer from proteins to nucleic acids does not occur.
Which of the following could be considered a violation of the Central Dogma?
I. Synthesis of DNA on an RNA template by reverse transcriptase.
II. Gene transcription being activated by a protein binding to regulatory sequences.
III. Editing of RNA transcripts by the insertion and deletion of ribonucleotides.
IV. A polynucleotide polymerase specifically synthesizing a gene encoding itself from free deoxyribonucleotides.
a. I
b. IV
c. II and III
d. None of the above

2. (1 point) The coding ratio in all known organisms is three, i.e. three nucleotides specify one amino acid. If DNA were to exclusively consist of only A-T base  pairs, what would the minimum coding ratio be assuming that there are only 20 amino acids to be encoded?
a. Two
b. Three
c. Four
d. Five

3. (1 point) The order of permeability for the following molecules across the plasma membrane will be:
a. Cholesterol < Glycerol < Water
b. Glycerol < Water < Cholesterol 
c. Water < Cholesterol < Glycerol
d. Cholesterol < Water < Glycerol

4. (1 point) Mammalian sulfite oxidase is the last enzyme in the pathway for degradation of sulfur- containing amino acids. Sulfite oxidase catalyses the oxidation of sulfite to sulfate, using the heme containing protein, cytochrome C, as an electron acceptor.
SO3^2- + 2 cytochrome C_oxidised + H2O ↔ SO4^2- + 2cytochrome C_reduced + 2 H⁺
Amino acid that is most likely to be present at the substrate binding site of this enzyme is:

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